Milhollen, M.A.: search on Z-Library

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1

Roger Fenton, Photographer of the Crimean War

Hirst Milhollen

Journal:

Quarterly Journal of Current Acquisitions

Year:

1946

Language:

english

File:

PDF, 1.20 MB

english, 1946

2

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Soucy, Teresa A., Smith, Peter G., Milhollen, Michael A., Berger, Allison J., Gavin, James M., Adhikari, Sharmila, Brownell, James E., Burke, Kristine E., Cardin, David P., Critchley, Stephen

Journal:

Year:

2009

Language:

english

File:

PDF, 528 KB

english, 2009

3

Mechanistic Studies of Substrate-assisted Inhibition of Ubiquitin-activating Enzyme by Adenosine Sulfamate Analogues

Chen, J. J., Tsu, C. A., Gavin, J. M., Milhollen, M. A., Bruzzese, F. J., Mallender, W. D., Sintchak, M. D., Bump, N. J., Yang, X., Ma, J.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

4

356 POSTER MLN4924, a potent and novel small molecule inhibitor of Nedd8 activating enzyme, induces DNA re-replication and apoptosis in cultured human tumor cells

M. Milhollen, U. Narayanan, B. Amidon, A. Berger, S. Langston, T. Soucy, P. Smith

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

5

Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolution

Malashkevich, V. N., Schneider, B. J., McNally, M. L., Milhollen, M. A., Pang, J. X., Kim, P. S.

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 447 KB

english, 1999

6

561 Nonclinical characterization of the first in class investigational ubiquitin activating enzyme inhibitor MLN7243 in cellular and in vivo models of cancer in support of a phase I study

Milhollen, M., Hyer, M., Ciavarri, J., Traore, T., Sappal, D., Huck, J., Shi, J., Duffy, J., Gavin, J., Brownell, J., Yang, Y., Stringer, B., Ishii, Y., Koenig, E., Lublinsky, A., Griffin, R., Xia, C.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 74 KB

english, 2014

7

Mathew B. Brady Collection

Hirst Milhollen

Journal:

Quarterly Journal of Current Acquisitions

Year:

1944

Language:

english

File:

PDF, 441 KB

english, 1944

8

85 POSTER Pharmacodynamic and efficacy relationship of MLN4924, a novel small molecule inhibitor of Nedd8-activating enzyme, in human xenograft tumors grown in immunocompromised mice

A. Berger, J. Yu, J. Garnsey, M. Milhollen, J. Zhang, T. Traore, L. Tou, A. McDonald, K. Burke, P.G. Smith

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

9

The Brady-Handy Collection

Hirst D. Milhollen

Journal:

Quarterly Journal of Current Acquisitions

Year:

1956

Language:

english

File:

PDF, 1.03 MB

english, 1956

10

IS LOWER DOSE ORAL ANTICOAGULATION AS EFFECTIVE AS STANDARD DOSE ORAL ANTICOAGULATION?

LoCicero, Richard, Berdeaux, Donald, Klein, Kevin, Koch, Maureen, Oberneufmann, Nancy, Milhollen, James, Brehm, Walter

Journal:

Southern Medical Journal

Year:

1993

File:

PDF, 118 KB

1993

11

286 MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor, Induces Differentiation in Acute Myelogenous Leukemia Cell Lines

Thomas, M.P., Milhollen, M.A., Naryanan, U., McDonald, A., Fleming, M., Amidon, B., Manfredi, M., Smith, P.G., Berger, A.J.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

12

Inhibition of NEDD8-Activating Enzyme Induces Rereplication and Apoptosis in Human Tumor Cells Consistent with Deregulating CDT1 Turnover

Milhollen, M. A., Narayanan, U., Soucy, T. A., Veiby, P. O., Smith, P. G., Amidon, B.

Journal:

Cancer Research

Year:

2011

Language:

english

File:

PDF, 2.13 MB

english, 2011

13

Core Structure of the Envelope Glycoprotein GP2 from Ebola Virus at 1.9- angstrom Resolution

Vladimir N. Malashkevich, Brian J. Schneider, Margaret L. McNally, Michael A. Milhollen, James X. Pang and Peter S. Kim

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.84 MB

english, 1999

14

The angiogenesis inhibitor NM-3 is active against human NSCLC xenografts alone and in combination with docetaxel

Naoki Agata, Hiroko Nogi, Michael Bamberg, Michael Milhollen, Minying Pu, Steven Weitman, Surender Kharbanda, Donald Kufe

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 312 KB

english, 2005

15

Overcoming Platinum Resistance in Preclinical Models of Ovarian Cancer Using the Neddylation Inhibitor MLN4924

Jazaeri, A. A., Shibata, E., Park, J., Bryant, J. L., Conaway, M. R., Modesitt, S. C., Smith, P. G., Milhollen, M. A., Berger, A. J., Dutta, A.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 828 KB

english, 2013

16

NEDD8-Targeting Drug MLN4924 Elicits DNA Rereplication by Stabilizing Cdt1 in S Phase, Triggering Checkpoint Activation, Apoptosis, and Senescence in Cancer Cells

Lin, J. J., Milhollen, M. A., Smith, P. G., Narayanan, U., Dutta, A.

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

17

577 Characterization of the cellular mechanism of action of the first in class investigational inhibitor of the Ubiquitin Activating Enzyme, MLN7243

Milhollen, M., Sappal, D., Duffy, J., Hoar, K., Huck, J., Sha, P., Koenig, E., Hyer, M., Ciavarri, J., Bence, N.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 60 KB

english, 2014

18

Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924

Blank, J. L., Liu, X. J., Cosmopoulos, K., Bouck, D. C., Garcia, K., Bernard, H., Tayber, O., Hather, G., Liu, R., Narayanan, U., Milhollen, M. A., Lightcap, E. S.

Journal:

Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

19

Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer

Nawrocki, S. T., Kelly, K. R., Smith, P. G., Espitia, C. M., Possemato, A., Beausoleil, S. A., Milhollen, M., Blakemore, S., Thomas, M., Berger, A., Carew, J. S.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

20

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

Hyer, Marc L, Milhollen, Michael A, Ciavarri, Jeff, Fleming, Paul, Traore, Tary, Sappal, Darshan, Huck, Jessica, Shi, Judy, Gavin, James, Brownell, Jim, Yang, Yu, Stringer, Bradley, Griffin, Robert, B

Journal:

Nature Medicine

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

21

Photographs

Alan Fern and Hirst D. Milhollen

Journal:

The Quarterly Journal of the Library of Congress

Year:

1966

Language:

english

File:

PDF, 444 KB

english, 1966

22

Treatment-Emergent Mutations in NAEβ Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924

Michael A. Milhollen, Michael P. Thomas, Usha Narayanan, Tary Traore, Jessica Riceberg, Benjamin S. Amidon, Neil F. Bence, Joseph B. Bolen, James Brownell, Lawrence R. Dick, Huay-Keng Loke, Alice A. M

Journal:

Year:

2012

Language:

english

File:

PDF, 1.65 MB

english, 2012

23

Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

James E. Brownell, Michael D. Sintchak, James M. Gavin, Hua Liao, Frank J. Bruzzese, Nancy J. Bump, Teresa A. Soucy, Michael A. Milhollen, Xiaofeng Yang, Anne L. Burkhardt, Jingya Ma, Huay-Keng Loke,

Journal:

Year:

2010

Language:

english

File:

PDF, 902 KB

english, 2010

24

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy

Soucy, T. A., Dick, L. R., Smith, P. G., Milhollen, M. A., Brownell, J. E.

Journal:

Year:

2010

Language:

english

File:

PDF, 291 KB

english, 2010

25

Identification of D-Peptide Ligands Through Mirror-Image Phage Display

Schumacher, T. N. M., Mayr, L. M., Minor, D. L., Milhollen, M. A., Burgess, M. W., Kim, P. S.

Journal:

Year:

1996

Language:

english

File:

PDF, 551 KB

english, 1996

26

255 Pre-clinical in vivo characterization of MLN7243, an investigational ubiquitin activating enzyme inhibitor, in solid tumor models

Traore, T., Huck, J.H., Shi, J.S., Sappal, D.S., Duffey, J.D., Yang, Y.Y., Kadakia, E.K., Chakravarty, A.C., Stringer, B.S., Ishii, Y.I., Griffin, R.G., Xia, C.X., Milhollen, M.M., Ciavarri, J.C., Fle

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

27

10.1038/13318

Redfield, Christina, Schulman, Brenda A., Milhollen, Michael A., Kim, Peter S., Dobson, Christopher M.

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 1.61 MB

english, 1999

28

The American Red Cross Collection of Photographs and Negatives

Hirst Milhollen

Journal:

Quarterly Journal of Current Acquisitions

Year:

1945

Language:

english

File:

PDF, 2.79 MB

english, 1945

29

Equal Effectiveness of Very—Low-Intensity Anticoagulation and Standard Low-Intensity Anticoagulation

KLEIN, KEVIN L., BERDEAUX, DONALD H., MILHOLLEN, JAMES D., HILDEN, JOHN T., OBERNUEFEMANN, NANCY J., KOCH, MAUREEN A., LoCICERO, RICHARD J., BREHM, WALTER T.

Journal:

Southern Medical Journal

Year:

1995

File:

PDF, 388 KB

1995

30

IS LOWER DOSE ORAL ANTICOAGULATION AS EFFECTIVE AS STANDARD DOSE ORAL ANTICOAGULATION?

LoCicero, Richard, Berdeaux, Donald, Klein, Kevin, Koch, Maureen, Oberneufmann, Nancy, Milhollen, James, Brehm, Walter

Journal:

Southern Medical Journal

Year:

1993

File:

PDF, 118 KB

1993

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